A new method to propagate defective HSV-1 vectors
نویسندگان
چکیده
منابع مشابه
A new method to determine a well-dispersed subsets of non-dominated vectors for MOMILP problem
Multi-objective optimization is the simultaneous consideration of two or more objective functions that are completely or partially inconflict with each other. The optimality of such optimizations is largely defined through the Pareto optimality. Multiple objective integer linear programs (MOILP) are special cases of multiple criteria decision making problems. Numerous algorithms have been desig...
متن کاملA new Defective Helper RNA to produce Sindbis virus that infects neurons but does not propagate
CC-BY-NC 4.0 International license peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was not. Abstract Recombinant Sindbis viruses are important tools in neuroscience because they combine rapid and high transgene expression with large payloads. Currently, two packaging systems are available for making neurotropic virus, but both prod...
متن کاملTargeting HSV amplicon vectors.
Several techniques have been developed to deliver DNA directly into mammalian cells, spanning in difficulty from simple mixing procedures to complex systems requiring expensive equipment. Viral vectors have proven able to deliver genes into mammalian cells with high efficiency and low toxicity. In particular, herpes simplex virus type-1 (HSV-1) amplicon vectors are well suited for gene transfer...
متن کاملAurintricarboxylic acid increases yield of HSV-1 vectors
Production of large quantities of viral vectors is crucial for the success of gene therapy in the clinic. There is a need for higher titers of herpes simplex virus-1 (HSV-1) vectors both for therapeutic use as well as in the manufacturing of clinical grade adeno-associated virus (AAV) vectors. HSV-1 yield increased when primary human fibroblasts were treated with anti-inflammatory drugs like de...
متن کاملa new method to determine a well-dispersed subsets of non-dominated vectors for momilp problem
multi-objective optimization is the simultaneous consideration of two or more objective functions that are completely or partially inconflict with each other. the optimality of such optimizations is largely defined through the pareto optimality. multiple objective integer linear programs (moilp) are special cases of multiple criteria decision making problems. numerous algorithms have been desig...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1988
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/16.12.5690